Senior Product Manager - Clinical Genomics Engineering

4w1 month ago

Natera

US · Full-time · $140,600 – $175,700

About this role

Natera delivers genetic risk assessment and diagnostic tests to patients through medical providers, and the Clinical Genomics Engineering organization builds software supporting complex, regulated workflows. As a Senior Product Manager, you will define and drive strategy for core components of the Results, Interpretation, and Reporting (RIR) platform.

Day-to-day, you will lead cross-functional alignment across engineering, clinical, quality, and downstream systems to ensure RIR components operate as a cohesive, scalable platform. You will identify systemic gaps, resolve cross-team tradeoffs, and drive architectural and workflow decisions that support long-term growth and regulatory compliance.

You will partner closely with software engineering, bioinformatics, clinical domain experts, quality, regulatory, and other product teams. This role initially owns one or more RIR software components or initiatives, with responsibility for defining long-term strategy and ensuring scalable architecture across user-facing applications, data contracts, and backend services.

As business needs evolve, your scope will expand to influence and coordinate across multiple RIR components, driving cohesive workflow design and platform-level scalability across Women’s Health, Oncology, and Organ Health. You will also mentor and raise the bar for product management within the organization.

Requirements

Proven experience defining product strategy for complex, regulated software platforms in clinical or genomics contexts
Strong technical acumen for collaborating with engineering leadership on architecture, data contracts, and backend services
Ability to translate business, clinical, and operational needs into clear, actionable product requirements
Experience driving cross-functional alignment and resolving systemic gaps across engineering, quality, and regulatory teams
Demonstrated ability to establish quantitative metrics for usability, performance, reliability, and adoption
Prior experience with variant interpretation, clinical review, or reporting workflows in a regulated environment
Familiarity with prioritization frameworks that balance regulatory risk, clinical impact, and technical scalability

Responsibilities

Define and drive multi-year product strategy and roadmap across one or more RIR components, ensuring alignment to clinical quality, regulatory requirements, and commercial scale objectives
Influence platform-level technical direction in partnership with engineering leadership
Partner closely with software engineering, bioinformatics, clinical domain experts, quality, regulatory, and other product teams
Translate business, clinical, and operational needs into clear, actionable product requirements
Define and evolve end-to-end user workflows, including UI/UX requirements and supporting backend functionality
Drive cross-team alignment on shared data contracts and workflow standards
Own measurable improvements in clinical workflow efficiency, reliability, and operational scalability
Establish prioritization frameworks that balance regulatory risk, clinical impact, technical scalability, and business outcomes across RIR investments

Benefits

Opportunity to shape foundational, regulated clinical software supporting Women’s Health, Oncology, and Organ Health
Work with a high-impact platform that directly influences clinical quality and commercial success
Collaborate with top-tier engineering, bioinformatics, and clinical domain experts
Mentorship and leadership development within a growing product management organization
Remote-friendly role with flexible location within the US